SCHEMBL16181542

SCHEMBL16181542

Cc1cc(Cl)cc(C(=O)NC(C)C)c1NC(=O)c1cc(CF)nn1-c1ncccc1Cl

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 2/20 0.35
DHODH Q02127 2/20 0.34
PDE4A P27815 2/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PDE4D Q08499 1/20 0.34
CAPN1 P07384 1/20 0.34
RECQL P46063 1/20 0.33
CNR1 P21554 2/20 0.33
EIF2S1 P05198 1/20 0.33
EIF2AK3 Q9NZJ5 1/20 0.33
TRPV1 Q8NER1 3/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
HPGD P15428 1/20 0.33
CNR2 P34972 1/20 0.33
DGAT2 Q96PD7 1/20 0.32
NTRK1 P04629 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15743795 0.93 CAPN1 (0.34) DHODHCAPN1RECQLCNR1TRPV1
SCHEMBL16433663 0.92 DHODH (0.36) MALT1DHODHPDE4APDE4BPDE4C
SCHEMBL15743808 0.92 DHODH (0.34) MALT1DHODHPDE4APDE4BPDE4C
SCHEMBL12113172 0.91 CAPN1 (0.34) MALT1DHODHPDE4APDE4BPDE4C
SCHEMBL16602288 0.91 DHODH (0.39) MALT1DHODHCAPN1
SCHEMBL15255583 0.90 SLC2A1 (0.34) MALT1DHODHCAPN1NTRK1
SCHEMBL12936147 0.89 KMT2A (0.38) MALT1DHODHRECQLCNR1MAPT
SCHEMBL782483 0.89 MALT1 (0.37) MALT1DHODHPDE4APDE4BPDE4C
SCHEMBL29039009 0.88 ANO1 (0.35) MALT1DHODHCNR1TRPV1CNR2
SCHEMBL12113166 0.87 F10 (0.37) MALT1DHODHCAPN1RECQLCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8865683-B2 Active compound combinations having insecticidal properties BAYER CROPSCIENCE AG (DE) 2014-10-21 US disclosed