Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | CPN1 | P15169 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29039480 | 1.00 | LCK (0.39) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL18281714 | 0.80 | METAP1 (0.42) | METAP1SLC1A3SLC1A2SLC1A1HPGD | |
| SCHEMBL19945731 | 0.78 | ALDH1A1 (0.42) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL29018457 | 0.78 | ALDH1A1 (0.42) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL8214327 | 0.77 | TET2 (0.43) | METAP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1734364 | 0.76 | METAP1 (0.47) | METAP1SLC1A3SLC1A2SLC1A1HPGD | |
| SCHEMBL25356227 | 0.75 | METAP1 (0.47) | ALDH1A1METAP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL25662123 | 0.75 | METAP1 (0.47) | ALDH1A1METAP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL4407623 | 0.75 | METAP1 (0.47) | ALDH1A1METAP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1565314 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TSHRSLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116262735-A | Novel oxo-pyridine compound and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-116262724-A | Novel oxo-pyridine compound and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |