Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 6/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 6/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 6/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 6/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.45 |
| ▸ | GSR | P00390 | 2/20 | 0.45 |
| ▸ | GRM8 | O00222 | 1/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25662123 | 1.00 | METAP1 (0.47) | METAP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25356227 | 1.00 | METAP1 (0.47) | METAP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL18774953 | 0.96 | METAP1 (0.52) | METAP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4714160 | 0.96 | METAP1 (0.52) | METAP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1224024 | 0.94 | METAP1 (0.55) | METAP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2877061 | 0.94 | METAP1 (0.55) | METAP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1768565 | 0.94 | METAP1 (0.55) | METAP1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL2033821 | 0.92 | METAP1 (0.53) | METAP1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL2029965 | 0.92 | METAP1 (0.53) | METAP1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL2029962 | 0.92 | METAP1 (0.53) | METAP1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | claimed |
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | disclosed |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20090180958-A1 | Diagnostic and therapeutic agents | KARYON-CTT LTD. (FI) | 2009-07-16 | — | — | US | disclosed |
| CN-101184769-A | Diagnostic and therapeutic agents | KARYON CTT LTD (FI) | 2008-05-21 | — | — | CN | disclosed |
| EP-1874800-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | Karyon-CTT Ltd (FI) | 2008-01-09 | — | — | EP | disclosed |
| US-20070258899-A1 | Diagnostic and therapeutic agents | KARYON-CTT LTD (FI) | 2007-11-08 | — | — | US | disclosed |
| WO-2007113385-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | KARYON-CTT LTD (FI) | 2007-10-11 | — | — | WO | disclosed |
| WO-2006114478-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | KARYON-CTT LTD (FI) | 2006-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | DNPEP, BCAT1, ANPEP | METAP1 40/4885GRIN2D 3459/4885GRIN3B 3203/4885 |
| US-20090180958-A1 | Diagnostic and therapeutic agents | TPX2, ZFX, ZYX | METAP1 34/4885GRIN2D 4380/4885GRIN3B 2612/4885 |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | PAICS, LNPEP, DNPEP | METAP1 88/4885GRIN2D 3446/4885GRIN3B 2424/4885 |
| US-20070258899-A1 | Diagnostic and therapeutic agents | YBX1, MLX, TPX2 | METAP1 2041/4885GRIN2D 4691/4885GRIN3B 4371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.