Butyric Acid

Butyric Acid

SCHEMBL29039804

CCCC(=O)O.O=C(O)C(O)CCO

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 3/20 0.58
KDM4A O75164 2/20 0.58
KDM4C Q9H3R0 2/20 0.58
KDM2A Q9Y2K7 2/20 0.58
TET3 O43151 1/20 0.58
HDAC1 Q13547 2/20 0.54
HDAC2 Q92769 2/20 0.54
FFAR3 O14843 1/20 0.54
HDAC3 O15379 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
GPR84 Q9NQS5 4/20 0.50
FFAR1 O14842 2/20 0.50
FFAR4 Q5NUL3 1/20 0.41
OR51E2 Q9H255 1/20 0.41
GABRP O00591 2/20 0.40
GABRD O14764 2/20 0.40
GABRA1 P14867 2/20 0.40
GABRB1 P18505 2/20 0.40
GABRG2 P18507 2/20 0.40
GABRB3 P28472 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyric Acid SCHEMBL6532700 0.87 TET2 (0.62) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL28139774 0.83 TET2 (0.58) TET2KDM4AKDM4CKDM2ATET3
Butyric Acid SCHEMBL28252594 0.83 GPR84 (0.67) TET2KDM4AKDM4CKDM2ATET3
Butyric Acid SCHEMBL28259845 0.83 OR51E2 (0.64) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL6834691 0.82
SCHEMBL3351656 0.82
SCHEMBL424600 0.82
Butyric Acid SCHEMBL3013187 0.80 FFAR3 (0.62) TET2KDM4AKDM4CKDM2ATET3
Butyric Acid SCHEMBL28295757 0.80 GPR84 (0.62) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL28585483 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111773388-B Combined application of A-nor-5 alpha androstane compound medicine and anticancer medicine 上海奥奇医药科技有限公司 2023-07-18 CN claimed
CN-111773388-B Combined application of A-nor-5 alpha androstane compound medicine and anticancer medicine 上海奥奇医药科技有限公司 2023-07-18 CN disclosed