SCHEMBL2903992

SCHEMBL2903992

C=C(C)C[Si](OC(C)C)(OC(C)C)OC(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1686167 0.79
SCHEMBL5861818 0.75 TSHR (0.39)
SCHEMBL537021 0.73
SCHEMBL1491037 0.70 HSD17B10 (0.33)
SCHEMBL29053275 0.70 GABRP (0.31)
SCHEMBL181290 0.68
SCHEMBL7758296 0.67
SCHEMBL1227637 0.67 TSHR (0.32)
SCHEMBL5489097 0.67
SCHEMBL6116020 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1994080-B1 LOW VOC EPOXY SILANE OLIGOMER AND COMPOSITIONS CONTAINING SAME MOMENTIVE PERFORMANCE MAT INC (US) 2019-01-16 EP claimed
WO-2013026823-A1 SEALING AGENT AND USE THEREOF AND SEALED METALLIC SUBSTRATE COVENTYA GMBH (DE) 2013-02-28 WO disclosed
EP-1194475-B1 WATERBORNE SILICONE ADHESIVES, SEALANTS AND COATINGS MOMENTIVE PERFORMANCE MAT INC (US) 2010-08-04 EP disclosed
EP-1194475-A1 WATERBORNE SILICONE ADHESIVES, SEALANTS AND COATINGS Crompton Corporation (US) 2002-04-10 EP disclosed
US-6319982-B1 POLYMER/CROSSLINKING SYSTEM WHICH IS COMPOSED OF A SELF CROSSLINKING RESIN COMPRISED OF A SILICONE FLUID MODIFIED WITH PENDANT OR TERMINAL SILANES CONTAINING HINDERED ALKOXY GROUPS CK WITCO CORPORATION 2001-11-20 US disclosed
WO-2001000711-A1 WATERBORNE SILICONE ADHESIVES, SEALANTS AND COATINGS CROMPTON CORPORATION (US) 2001-01-04 WO disclosed