Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 10/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333242 | 0.77 | NPC1 (0.47) | ALDH1A1HPGDNPC1KDM4ESMN1; SMN2 | |
| SCHEMBL1546514 | 0.75 | NPC1 (0.54) | ALDH1A1HPGDMAPK1NPC1KDM4E | |
| SCHEMBL2753064 | 0.73 | MAPK1 (0.55) | ALDH1A1HPGDMAPK1NPC1KDM4E | |
| SCHEMBL12964716 | 0.73 | KDM4E (0.83) | ALDH1A1HPGDMAPK1NPC1KDM4E | |
| SCHEMBL1660913 | 0.72 | SMN1; SMN2 (0.82) | ALDH1A1HPGDMAPK1NPC1KDM4E | |
| SCHEMBL242857 | 0.71 | RAB9A (0.47) | ALDH1A1HPGDMAPK1NPC1KDM4E | |
| SCHEMBL28795371 | 0.71 | CSNK2A1 (0.46) | HPGDNPC1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL8840880 | 0.71 | PDE4A (0.67) | ALDH1A1HPGDMAPK1NPC1KDM4E | |
| SCHEMBL5552360 | 0.71 | NPC1 (0.42) | ALDH1A1HPGDNPC1KDM4ESMN1; SMN2 | |
| SCHEMBL12626897 | 0.70 | NPC1 (0.84) | ALDH1A1HPGDMAPK1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |