Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 2/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 4/20 | 0.41 |
| ▸ | CCNC | P24863 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15415871 | 0.88 | MAOB (0.49) | VNN1PTGER3PDE1CCDK8CCNC | |
| SCHEMBL8296670 | 0.81 | PLAU (0.45) | VNN1PTGER3PDE1CNOTUMERCC1 | |
| SCHEMBL1759304 | 0.76 | TNKS (0.52) | VNN1PTGER3PDE1CCDK8CCNC | |
| SCHEMBL29794165 | 0.76 | TNKS (0.52) | VNN1PTGER3PDE1CCDK8CCNC | |
| SCHEMBL14302967 | 0.76 | VNN1 (0.45) | VNN1PTGER3PDE1CCDK8CCNC | |
| SCHEMBL20239415 | 0.76 | CDK8 (0.58) | VNN1PTGER3PDE1CCDK8CCNC | |
| SCHEMBL29819532 | 0.76 | CDK8 (0.58) | VNN1PTGER3PDE1CCDK8CCNC | |
| SCHEMBL4261983 | 0.75 | PDE1C (0.57) | VNN1PTGER3PDE1CCDK8CCNC | |
| SCHEMBL29491497 | 0.75 | PDE1C (0.57) | VNN1PTGER3PDE1CCDK8CCNC | |
| SCHEMBL29698372 | 0.75 | CCNC (0.65) | VNN1PTGER3PDE1CCDK8CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |