Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.52 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.52 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.52 |
| ▸ | VNN1 | O95497 | 1/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.49 |
| ▸ | FASN | P49327 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 3/20 | 0.47 |
| ▸ | CDK8 | P49336 | 2/20 | 0.46 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29794165 | 1.00 | TNKS (0.52) | TNKSTNKS2KDM2BKDM4CVNN1 | |
| SCHEMBL16595389 | 0.87 | VNN1 (0.49) | TNKSTNKS2KDM2BKDM4CVNN1 | |
| SCHEMBL30159516 | 0.86 | MAOB (0.56) | TNKSTNKS2KDM2BVNN1PTGER3 | |
| SCHEMBL20239415 | 0.86 | CDK8 (0.58) | TNKSTNKS2VNN1PTGER3FASN | |
| SCHEMBL1144709 | 0.86 | MAOB (0.56) | TNKSTNKS2KDM2BVNN1PTGER3 | |
| SCHEMBL29819532 | 0.86 | CDK8 (0.58) | TNKSTNKS2VNN1PTGER3FASN | |
| SCHEMBL19691125 | 0.85 | AR (0.55) | TNKSTNKS2VNN1PTGER3FASN | |
| SCHEMBL29503149 | 0.85 | AR (0.55) | TNKSTNKS2VNN1PTGER3FASN | |
| SCHEMBL12647579 | 0.83 | VNN1 (0.49) | TNKSTNKS2KDM2BVNN1PTGER3 | |
| SCHEMBL5396657 | 0.82 | HCAR3 (0.52) | PTGER3HCAR3KMOPLA2G4ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12258318-B2 | Synthesis method for 1-methyl-1H-indazole-6-carboxylic acid | ACCELA CHEMBIO CO., LTD. (CN) | 2025-03-25 | — | — | US | claimed |
| US-20220235010-A1 | SYNTHESIS METHOD FOR 1-METHYL-1H-INDAZOLE-6-CARBOXYLIC ACID | ACCELA CHEMBIO CO., LTD. (CN) | 2022-07-28 | — | — | US | claimed |
| WO-2020253533-A1 | SYNTHESIS METHOD FOR 1-METHYL-1H-INDAZOLE-6-CARBOXYLIC ACID | 韶远科技（上海)有限公司 | 2020-12-24 | — | — | WO | claimed |
| US-12297190-B2 | Modulators of STING (stimulator of interferon genes) | PFIZER INC. (US) | 2025-05-13 | — | — | US | disclosed |
| US-20250136592-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | BRIDGE MEDICINES | 2025-05-01 | — | — | US | disclosed |
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |
| US-12258318-B2 | Synthesis method for 1-methyl-1H-indazole-6-carboxylic acid | ACCELA CHEMBIO CO., LTD. (CN) | 2025-03-25 | — | — | US | disclosed |
| US-12258318-B2 | Synthesis method for 1-methyl-1H-indazole-6-carboxylic acid | ACCELA CHEMBIO CO., LTD. (CN) | 2025-03-25 | — | — | US | disclosed |
| US-12258318-B2 | Synthesis method for 1-methyl-1H-indazole-6-carboxylic acid | ACCELA CHEMBIO CO., LTD. (CN) | 2025-03-25 | — | — | US | disclosed |
| CN-115515956-B | Benzimidazole derivative, and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| EP-3674298-B9 | SUBSTITUTED INDAZOLES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL FORMULATIONS CONTAINING THEM, AND THEIR USE FOR THE PREPARATION OF MEDICAMENTS | Bayer Pharma AG (DE) | 2024-06-19 | — | — | EP | disclosed |
| US-20100105663-A1 | 2-(HETEROARYL) ALKYL INDAZOLE 6-PHENYL AND THIENYL METHYL AMIDE AS THROMBIN INHIBITORS | BAYER HEALTHCARE AG (DE) | 2010-04-29 | — | — | US | disclosed |
| EP-2141147-A1 | ORNITHINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2010-01-06 | — | — | EP | disclosed |
| US-20090270435-A1 | Spiroketone Acetyl-CoA Carboxylase Inhibitors | CORBETT JEFFREY WAYNE | 2009-10-29 | — | — | US | disclosed |
| EP-2097420-A1 | SPIROKETONE ACETYL-COA CARBOXYLASE INHIBITORS | Pfizer Products Inc. (US) | 2009-09-09 | — | — | EP | disclosed |
| EP-2044031-A1 | 2-(HETEROARYL) ALKYL INDAZOLE 6-PHENYL AND THIENYL METHYL AMIDE AS THROMBIN INHIBITORS | Bayer HealthCare AG (DE) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008065508-A1 | SPIROKETONE ACETYL-COA CARBOXYLASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |
| WO-2008006479-A1 | 2-(HETEROARYL) ALKYL INDAZOLE 6-PHENYL AND THIENYL METHYL AMIDE AS THROMBIN INHIBITORS | BAYER HEALTHCARE AG (DE) | 2008-01-17 | — | — | WO | disclosed |
| WO-1992022536-A1 | VINYLIMIDAZOLES, VINYLTRIAZOLES AND VINYLTETRAZOLES WITH A BICYCLIC SUBSTITUENT GROUP | SCHERING AKTIENGESELLSCHAFT, BERLIN UND BERGKAMEN (DE) | 1992-12-23 | — | — | WO | disclosed |
| EP-0518457-A1 | Bicyclic substituted vinylimidazoles, -triazoles and -tetrazoles | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12297190-B2 | Modulators of STING (stimulator of interferon genes) | STING1, IRF3, CGAS | TNKS 487/4885TNKS2 492/4885KDM2B 4239/4885 |
| US-20100105663-A1 | 2-(HETEROARYL) ALKYL INDAZOLE 6-PHENYL AND THIENYL METHYL AMIDE AS THROMBIN INHIBITORS | F2, TFPI, PLAT | TNKS 240/4885TNKS2 418/4885KDM2B 1789/4885 |
| US-20090270435-A1 | Spiroketone Acetyl-CoA Carboxylase Inhibitors | ACACA, PC, ACACB | TNKS 1181/4885TNKS2 1779/4885KDM2B 2736/4885 |
| US-20250136592-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | MLLT3, MLLT1, YEATS2 | TNKS 1074/4885TNKS2 1044/4885KDM2B 276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.