Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | BRD4 | O60885 | 2/20 | 0.65 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20660929 | 0.81 | SMN1; SMN2 (0.58) | MEN1KMT2AATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL1422842 | 0.80 | SMN1; SMN2 (0.71) | MEN1KMT2AATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL1119999 | 0.80 | SMN1; SMN2 (0.71) | MEN1KMT2AATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL7539164 | 0.79 | SMN1; SMN2 (0.65) | MEN1KMT2AATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL23846427 | 0.79 | SMN1; SMN2 (1.00) | MEN1KMT2AATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL31060459 | 0.79 | SMN1; SMN2 (1.00) | MEN1KMT2AATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL20116594 | 0.75 | SMN1; SMN2 (0.68) | MEN1KMT2AATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL20660930 | 0.75 | SMN1; SMN2 (0.68) | MEN1KMT2AATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL16131037 | 0.75 | MAOB (0.60) | HDAC6HDAC1HDAC8 | |
| SCHEMBL4190022 | 0.75 | SMN1; SMN2 (0.63) | MEN1KMT2AATMSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |