Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | BRD4 | O60885 | 2/20 | 0.63 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4859467 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL4860594 | 0.81 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL27593085 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL1119999 | 0.79 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL1422842 | 0.79 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL5981648 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL23846427 | 0.77 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL31060459 | 0.77 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL29040367 | 0.75 | MEN1 (0.67) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL7539164 | 0.75 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119118925-B | Preparation method and application of benzimidazole-2-ketone derivative | 中国人民解放军陆军军医大学 | 2025-05-27 | — | — | CN | claimed |
| CN-119118925-A | Preparation method and application of benzimidazole-2-ketone derivative | 中国人民解放军陆军军医大学 | 2024-12-13 | — | — | CN | claimed |
| CN-119118925-B | Preparation method and application of benzimidazole-2-ketone derivative | 中国人民解放军陆军军医大学 | 2025-05-27 | — | — | CN | disclosed |
| CN-119118925-A | Preparation method and application of benzimidazole-2-ketone derivative | 中国人民解放军陆军军医大学 | 2024-12-13 | — | — | CN | disclosed |
| US-20090130165-A1 | MIF Inhibitors | CORTICAL PTY LTD | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090130165-A1 | MIF Inhibitors | MIF, MMP12, IL4 | SMN1; SMN2 4311/4885ALDH1A1 780/4885HSD17B10 2179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.