Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870206 | 0.78 | HSP90AA1 (0.34) | HPGDPKMAOC3SRCKDM4E | |
| SCHEMBL7672194 | 0.78 | AGXT (0.46) | HPGDPDE10ASRCKDM4EALDH1A1 | |
| SCHEMBL22978654 | 0.71 | GRM5 (0.41) | HPGDPKMAOC3SRCMAPT | |
| SCHEMBL26260178 | 0.70 | AGXT (0.39) | HPGDSRCKDM4EALDH1A1RECQL | |
| SCHEMBL27950710 | 0.68 | KDM4E (0.36) | HPGDSRCMAPTKDM4EALDH1A1 | |
| SCHEMBL30452378 | 0.68 | EGFR (0.32) | HPGDSRC | |
| SCHEMBL24257705 | 0.68 | EGFR (0.32) | HPGDSRC | |
| SCHEMBL24257758 | 0.67 | POLB (0.41) | MAPTLMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL21749932 | 0.67 | PDE4A (0.43) | HPGDPDE10ASRCMAPTPDE4A | |
| SCHEMBL20944235 | 0.67 | PKM (0.38) | HPGDPKMMAPTPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |