Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | USP8 | P40818 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | AGXT | P21549 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257705 | 1.00 | EGFR (0.32) | EGFRERBB2SRCGPR35USP8 | |
| SCHEMBL26260178 | 0.81 | AGXT (0.39) | SRCUSP8USP7HPGDAGXT | |
| SCHEMBL28025805 | 0.76 | ALOX5AP (0.36) | SRC | |
| SCHEMBL7672194 | 0.74 | AGXT (0.46) | SRCUSP8USP7HPGDAGXT | |
| SCHEMBL27955259 | 0.73 | CA2 (0.34) | CA2CA4AGXTHTT | |
| SCHEMBL2238931 | 0.73 | PLCG1 (0.36) | USP8USP7CA2CA4HTT | |
| SCHEMBL30527595 | 0.73 | PLCG1 (0.36) | USP8USP7CA2CA4HTT | |
| SCHEMBL20704245 | 0.72 | FYN (0.38) | USP7CA2CA4AGXTHTT | |
| SCHEMBL20704234 | 0.72 | CA2 (0.33) | CA2CA4HPGDAGXT | |
| SCHEMBL1846308 | 0.70 | HPGDS (0.39) | EGFRERBB2USP8USP7HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196466-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Akebia Therapeutics Inc. (US) | 2023-06-21 | — | — | EP | disclosed |