SCHEMBL29040564

SCHEMBL29040564

C#CC(OC(=O)OC(C#C)c1ccc2ccccc2c1)c1ccc2ccccc2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UGT2B7 P16662 1/20 0.43
MMP9 P14780 1/20 0.40
AOC3 Q16853 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ATM Q13315 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38
AKR1C3 P42330 3/20 0.37
AKR1C2 P52895 3/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
GLA P06280 1/20 0.36
PTGS1 P23219 2/20 0.36
PTGS2 P35354 2/20 0.36
CDC42 P60953 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11353078 0.84 L3MBTL1 (0.47) UGT2B7MEN1KMT2AL3MBTL1
SCHEMBL28685361 0.81 UGT2B7 (0.46) UGT2B7AOC3MEN1KMT2AATM
SCHEMBL29040565 0.79 CYP2D6 (0.40) MEN1KMT2ACES2CES1TDP1
SCHEMBL11356023 0.77 UGT2B7 (0.40) UGT2B7MMP9AOC3MEN1KMT2A
SCHEMBL7126500 0.72 UGT2B7 (0.45) UGT2B7MMP9AOC3MEN1KMT2A
SCHEMBL11357180 0.72 UGT2B7 (0.57) UGT2B7AOC3MEN1KMT2AATM
SCHEMBL30760973 0.72 UGT2B7 (0.57) UGT2B7AOC3MEN1KMT2AATM
SCHEMBL31238799 0.71 KMT2A (0.47) MEN1KMT2AMTNR1AMTNR1BAKR1C3
SCHEMBL10543638 0.70 UGT2B7 (0.39) UGT2B7AOC3MEN1KMT2AATM
SCHEMBL31238878 0.69 HSD17B10 (0.39) AOC3MEN1KMT2ATDP1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116444370-A Preparation method of alpha, beta-unsaturated carboxylic acid derivative 大连理工常熟研究院有限公司 2023-07-18 CN disclosed