Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Benzodiazepine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzodiazepine SCHEMBL10694670 | 0.89 | MAPT (0.38) | GAAMAPTKDM4EMAPK1P2RX4 | |
| Benzodiazepine SCHEMBL11469198 | 0.87 | MAPT (0.36) | GAAMAPTP2RX4 | |
| Glucuronic Acid SCHEMBL29219575 | 0.86 | CYP1A2 (0.31) | — | |
| Benzodiazepine SCHEMBL29151800 | 0.86 | MAPT (0.35) | GAAMAPTP2RX4 | |
| Benzodiazepine SCHEMBL14740757 | 0.86 | MAPT (0.35) | GAAMAPTLMNAMAPK1TSHR | |
| Benzodiazepine SCHEMBL27880113 | 0.85 | P2RX4 (0.34) | GAAMAPTP2RX4 | |
| Benzodiazepine SCHEMBL4971764 | 0.84 | MAPT (0.36) | GAAMAPTP2RX4 | |
| Benzodiazepine SCHEMBL1574261 | 0.84 | MAPT (0.36) | GAAMAPTLMNAMAPK1TSHR | |
| Benzodiazepine SCHEMBL27786695 | 0.84 | MAPT (0.36) | GAAMAPTP2RX4 | |
| Benzodiazepine SCHEMBL28436814 | 0.84 | GAA (0.41) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745293-A | Salts and crystals | 金奥克斯治疗有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116507327-A | Chewable formulations | 礼蓝动物保健有限公司 | 2023-07-28 | — | — | CN | disclosed |