Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30508272 | 0.94 | PRMT5 (0.39) | PRMT5WDR77HSD17B3CARM1HRH3 | |
| SCHEMBL28587390 | 0.84 | CARM1 (0.41) | HSD17B3CARM1HRH3ABHD6ASIC3 | |
| SCHEMBL4573212 | 0.83 | CARM1 (0.42) | PRMT5HSD17B3CARM1HRH3ABHD6 | |
| SCHEMBL26963045 | 0.82 | HRH3 (0.47) | HSD17B3CARM1HRH3ABHD6ASIC3 | |
| SCHEMBL12682855 | 0.82 | CHRM2 (0.43) | PRMT5WDR77HRH3 | |
| SCHEMBL24697332 | 0.79 | HRH3 (0.49) | HRH3ASIC3FAAH | |
| SCHEMBL30658395 | 0.79 | ASIC3 (0.44) | PRMT5HSD17B3CARM1HRH3ABHD6 | |
| SCHEMBL26963061 | 0.79 | ASIC3 (0.44) | PRMT5HSD17B3CARM1HRH3ABHD6 | |
| SCHEMBL26962994 | 0.78 | FAAH (0.45) | HSD17B3ADRA1AABHD6FAAH | |
| SCHEMBL29113468 | 0.77 | CARM1 (0.39) | PRMT5HSD17B3CARM1ABHD6ASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |