Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28424129 | 0.80 | NPC1 (0.60) | KDM4ENPC1RAB9AMEN1KMT2A | |
| SCHEMBL15474792 | 0.80 | SYK (0.46) | KDM4EALDH1A1SYKTSHRNPC1 | |
| SCHEMBL826085 | 0.78 | NPC1 (0.54) | KDM4EALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL15474937 | 0.78 | SYK (0.44) | KDM4EALDH1A1SYKTSHRNPC1 | |
| SCHEMBL15475025 | 0.76 | ALDH1A1 (0.54) | KDM4EALDH1A1SYKTSHRNPC1 | |
| SCHEMBL3805844 | 0.75 | KDR (0.48) | KDM4EALDH1A1SYKTSHRNPC1 | |
| SCHEMBL29042126 | 0.75 | MAPT (0.44) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11752723 | 0.74 | TSHR (0.55) | KDM4EALDH1A1SYKTSHRCA12 | |
| SCHEMBL521854 | 0.74 | LTA4H (0.63) | KDM4EALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL28431640 | 0.74 | NPC1 (0.52) | KDM4EALDH1A1TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |