Trichloroacetic Acid

Trichloroacetic Acid

SCHEMBL2904243

CN(C)C.O=C(O)C(Cl)(Cl)Cl

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.71
ALDH1A1 P00352 3/20 0.71
TP53 P04637 1/20 0.71
TDP1 Q9NUW8 1/20 0.42
CYP1A2 P05177 1/20 0.32
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trichloroacetic Acid SCHEMBL6912948 0.89
Trichloroacetic Acid SCHEMBL8995195 0.85
Trichloroacetic Acid SCHEMBL5311061 0.84 TSHR (1.00) TSHRALDH1A1TP53TDP1CYP1A2
Trichloroacetic Acid SCHEMBL3220 0.84
Trichloroacetic Acid SCHEMBL1331160 0.84
Trichloroacetic Acid SCHEMBL38661501 0.84
Trichloroacetic Acid SCHEMBL1331955 0.84
Trichloroacetic Acid SCHEMBL10745837 0.84
Trichloroacetic Acid SCHEMBL10493657 0.84 TSHR (1.00) TSHRALDH1A1TP53TDP1CYP1A2
Trichloroacetic Acid SCHEMBL7710933 0.82 ALDH1A1 (0.56) TSHRALDH1A1TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0625176-B1 MOISTURE CURABLE POLYSILOXANE RELEASE COATING COMPOSITIONS MINNESOTA MINING & MFG (US) 1996-12-04 EP claimed
EP-0560059-B1 Abrasive articles including a crosslinked siloxane MINNESOTA MINING & MFG (US) 1996-02-28 EP claimed
EP-0625176-A1 MOISTURE CURABLE POLYSILOXANE RELEASE COATING COMPOSITIONS. MINNESOTA MINING & MFG (US) 1994-11-23 EP claimed
US-5286815-A Containing an acid catalyst MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-02-15 US claimed
EP-0560059-A2 Abrasive articles including a crosslinked siloxane MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-09-15 EP claimed
WO-1993016142-A1 MOISTURE CURABLE POLYSILOXANE RELEASE COATING COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-19 WO claimed
US-5213589-A Reduced loading, reduced transfer of pressure sensitive adhesive when stacked or rolled MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-05-25 US claimed
US-20260026976-A1 FLUID-MANAGING MEDICAL ADHESIVE ARTICLES WITH MICROSTRUCTURED SURFACES SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-29 US disclosed
US-12453659-B2 Fluid-managing medical adhesive articles with microstructured surfaces SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-10-28 US disclosed
EP-3676332-B1 SOLID SILOXANE POLYMERS AS DELIVERY AGENTS FOR SILOXANE TACKIFYING RESINS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-01-29 EP disclosed
EP-3775085-B1 SILOXANE-BASED GEL ADHESIVES SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-07-24 EP disclosed
US-11492491-B2 Solid siloxane polymers as delivery agents for siloxane tackifying resins 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-11-08 US disclosed
US-20220257424-A1 FLUID-MANAGING MEDICAL ADHESIVE ARTICLES WITH MICROSTRUCTURED SURFACES SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2022-08-18 US disclosed
WO-1996034028-A1 TACKIFIED POLYDIORGANOSILOXANE OLIGOUREA SEGMENTED COPOLYMERS AND A PROCESS FOR MAKING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-10-31 WO disclosed
EP-0560059-B1 Abrasive articles including a crosslinked siloxane MINNESOTA MINING & MFG (US) 1996-02-28 EP disclosed
EP-0625176-A1 MOISTURE CURABLE POLYSILOXANE RELEASE COATING COMPOSITIONS. MINNESOTA MINING & MFG (US) 1994-11-23 EP disclosed
US-5286815-A Containing an acid catalyst MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-02-15 US disclosed
EP-0560059-A2 Abrasive articles including a crosslinked siloxane MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-09-15 EP disclosed
WO-1993016142-A1 MOISTURE CURABLE POLYSILOXANE RELEASE COATING COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-19 WO disclosed
US-5213589-A Reduced loading, reduced transfer of pressure sensitive adhesive when stacked or rolled MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260026976-A1 FLUID-MANAGING MEDICAL ADHESIVE ARTICLES WITH MICROSTRUCTURED SURFACES EPCAM, CDH1, ICAM1 TSHR 1695/4885ALDH1A1 1075/4885TP53 1901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.