Levodropropizine

Levodropropizine

SCHEMBL29043

OC[C@@H](O)CN1CCN(c2ccccc2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 1.00
ADRA2B P18089 1/20 1.00
ADRA2C P18825 1/20 1.00
KMT2A Q03164 3/20 0.66
MEN1 O00255 2/20 0.66
MAPT P10636 5/20 0.64
TSHR P16473 1/20 0.62
IGF1R P08069 1/20 0.57
MAPK1 P28482 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
KDM4E B2RXH2 2/20 0.57
ALDH1A1 P00352 2/20 0.57
GAA P10253 1/20 0.57
GFER P55789 1/20 0.57
TDP1 Q9NUW8 1/20 0.56
ADRA1B P35368 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dropropizine SCHEMBL8379428 1.00 ADRA2A (1.00) ADRA2AADRA2BADRA2CKMT2AMEN1
Dropropizine SCHEMBL93975 1.00 ADRA2A (1.00) ADRA2AADRA2BADRA2CKMT2AMEN1
Dropropizine SCHEMBL27495915 0.98 ADRA2A (0.97) ADRA2AADRA2BADRA2CKMT2AMEN1
Dropropizine SCHEMBL10445730 0.91 ADRA2A (0.83) ADRA2AADRA2BADRA2CKMT2AMEN1
Dropropizine SCHEMBL10445733 0.90 ADRA2A (0.81) ADRA2AADRA2BADRA2CKMT2AMEN1
Dropropizine SCHEMBL10445975 0.90 ADRA2A (0.81) ADRA2AADRA2BADRA2CKMT2AMEN1
Dropropizine SCHEMBL10446140 0.90 ADRA2A (0.81) ADRA2AADRA2BADRA2CKMT2AMEN1
Dropropizine SCHEMBL10446134 0.90 ADRA2A (0.81) ADRA2AADRA2BADRA2CKMT2AMEN1
Dropropizine SCHEMBL10445732 0.90 ADRA2A (0.81) ADRA2AADRA2BADRA2CKMT2AMEN1
Dropropizine SCHEMBL10445734 0.85 ADRA2A (0.72) ADRA2AADRA2BADRA2CKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1574 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250255781-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-08-14 US claimed
WO-2025150072-A1 A STABLE ORAL PRO-DISPERSION FORMULATION AND IMPLEMENTATIONS THEREOF PULSE PHARMACEUTICALS PVT LTD (IN) 2025-07-17 WO claimed
US-20250191770-A1 COMPUTERIZED DECISION SUPPORT TOOL AND MEDICAL DEVICE FOR RESPIRATORY CONDITION MONITORING AND CARE PFIZER INC. (US) 2025-06-12 US claimed
US-12296043-B2 Liquisoft capsules PATHEON SOFTGELS INC. (US) 2025-05-13 US claimed
CN-119947988-A Porous carbon material, method for producing same, positive electrode comprising carbon material as positive electrode active material, and lithium secondary battery 株式会社LG新能源 2025-05-06 CN claimed
CN-116381123-B Method for determining substances contained in levodropropizine raw material, capsule and tablet 湖南省药品检验检测研究院 2025-04-25 CN claimed
EP-4510999-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS Bristol-Myers Squibb Company (US) 2025-02-26 EP claimed
CN-119322127-A Method for detecting related substances of levodropropizine oral solution 南京斯泰尔医药科技有限公司 2025-01-17 CN claimed
US-20240165020-A1 LIQUISOFT CAPSULES PATHEON SOFTGELS INC (US) 2024-05-23 US claimed
EP-4360653-A2 LIQUISOFT CAPSULES Patheon Softgels Inc. (US) 2024-05-01 EP claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
CN-1520820-A Slow release levodropropizine pharmaceutical composition 王志刚 2004-08-18 CN claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
US-6069172-A ADMINISTERING THE ENANTIOMER (R)-KETOPROFEN AND OF ITS SALTS WITH SUITABLE ORGANIC AND INORGANIC BASES IN THE THERAPY OF NEUTROPHIL-DEPENDENT DISEASES DOMPE' SPA (IT) 2000-05-30 US claimed
EP-0935961-A2 (R)-2-(3-Benzoylphenyl)propionic acid salts and pharmaceutical preparations containing them Dompé S.P.A. (IT) 1999-08-18 EP claimed
EP-0575776-B1 A process for the preparation of enantiomers of dropropizine BIDACHEM SPA (IT) 1999-03-31 EP claimed
EP-0703893-A1 SALTS OF 2-(3-BENZOYLPHENYL) PROPIONIC ACID WITH ACHIRAL AND CHIRAL ORGANIC BASES AND PHARMACEUTICAL COMPOSITIONS THEREOF DOMPE FARMACEUTICI S.P.A. (IT) 1996-04-03 EP claimed
WO-1994020449-A1 SALTS OF 2-(3-BENZOYLPHENYL)PROPIONIC ACID WITH ACHIRAL AND CHIRAL ORGANIC BASES AND PHARMACEUTICAL COMPOSITIONS THEREOF DOMPE'FARMACEUTICI SPA (IT) 1994-09-15 WO claimed
EP-0348713-A1 (R,S)-3-(4-phenyl-1-piperazinyl)-1,2-propanediol salts DOTT. FORMENTI S.P.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) 1990-01-03 EP claimed