⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL744918 | 0.79 | HPGDS (0.38) | — | |
| SCHEMBL2629375 | 0.69 | SMYD3 (0.47) | — | |
| SCHEMBL8627364 | 0.65 | — | — | |
| SCHEMBL148962 | 0.65 | — | — | |
| SCHEMBL4488631 | 0.65 | — | — | |
| SCHEMBL25436427 | 0.64 | POLB (0.36) | — | |
| SCHEMBL5011783 | 0.64 | PKM (0.39) | — | |
| SCHEMBL19951035 | 0.64 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL12471584 | 0.64 | HDAC6 (0.35) | — | |
| SCHEMBL15759484 | 0.62 | POLB (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261454-A | Imidazopiperazine inhibitors of transcriptional activator proteins | 德州大学系统董事会 | 2023-06-13 | — | — | CN | disclosed |