Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.52 |
| ▸ | PI4KA | P42356 | 3/20 | 0.52 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.52 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.47 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.47 |
| ▸ | AHCY | P23526 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2904399 | 0.89 | ADORA2A (0.54) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL2906673 | 0.84 | CCNE1 (0.53) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL4279920 | 0.83 | ADORA2A (0.48) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL5665238 | 0.81 | FGFR1 (0.56) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL3293448 | 0.81 | FGFR1 (0.56) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL4279921 | 0.80 | CYP3A4 (0.47) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL2906656 | 0.79 | ADORA2A (0.55) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL13328630 | 0.78 | CYP3A4 (0.48) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL2943371 | 0.77 | CCNE1 (0.39) | — | |
| SCHEMBL2912070 | 0.77 | CYP3A4 (0.49) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |