Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 5/20 | 0.53 |
| ▸ | CDK2 | P24941 | 5/20 | 0.53 |
| ▸ | CDK1 | P06493 | 4/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.42 |
| ▸ | AHCY | P23526 | 1/20 | 0.37 |
| ▸ | HINT1 | P49773 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | PDE8A | O60658 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906676 | 0.89 | CDK1 (0.55) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL2943371 | 0.88 | CCNE1 (0.39) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL2904396 | 0.84 | ADORA2A (0.52) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL4273209 | 0.81 | CDK1 (0.46) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL3294539 | 0.81 | CDK1 (0.46) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL2942557 | 0.81 | KDM4E (0.42) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL2943375 | 0.77 | CCNE1 (0.40) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL4270424 | 0.73 | CCNE1 (0.36) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL2904399 | 0.72 | ADORA2A (0.54) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL4963642 | 0.72 | CCNE1 (0.62) | CCNE1CDK2CDK1CCNB1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |