Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 4/20 | 0.39 |
| ▸ | CDK2 | P24941 | 4/20 | 0.39 |
| ▸ | CDK1 | P06493 | 3/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 8/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2943375 | 0.89 | CCNE1 (0.40) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL2906673 | 0.88 | CCNE1 (0.53) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL4270424 | 0.84 | CCNE1 (0.36) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL3288110 | 0.83 | POLB (0.38) | CCNE1CDK2CDK1CCNB1CYP3A4 | |
| SCHEMBL6053864 | 0.83 | POLB (0.38) | CCNE1CDK2CDK1CCNB1CYP3A4 | |
| SCHEMBL4270429 | 0.82 | POLB (0.35) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL4278199 | 0.82 | CCNE1 (0.34) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL2942557 | 0.81 | KDM4E (0.42) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL2990364 | 0.78 | FAP (0.35) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL2904396 | 0.77 | ADORA2A (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |