Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | TP53 | P04637 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29044124 | 0.90 | MAPT (0.52) | MAPTTP53ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL29044128 | 0.88 | MAPT (0.59) | MAPTTP53ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL29044109 | 0.86 | ALDH1A1 (0.50) | MAPTTP53ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL29044117 | 0.82 | ALDH1A1 (0.48) | MAPTTP53ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL29044116 | 0.82 | MAPT (0.52) | MAPTTP53ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL28683361 | 0.81 | MAPT (0.84) | MAPTTP53ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL29044119 | 0.80 | MAPT (0.59) | MAPTTP53ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL28705989 | 0.78 | MAPT (0.82) | MAPTTP53ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL29044113 | 0.78 | MAPT (0.57) | MAPTTP53ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL28705172 | 0.78 | MAPT (0.81) | MAPTTP53ALDH1A1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057626-B | Indole-2, 3-dione derivative, preparation method thereof and anti-liver cancer drug for inhibiting RECQL4 specific expression | 山东第一医科大学(山东省医学科学院) | 2023-06-30 | — | — | CN | disclosed |