Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28696462 | 0.89 | ALDH1A1 (0.59) | ALDH1A1MAPTUSP2MAPK1HSD17B10 | |
| SCHEMBL29044127 | 0.86 | ALDH1A1 (0.62) | ALDH1A1MAPTUSP2ALOX15MAPK1 | |
| SCHEMBL28686541 | 0.84 | ALDH1A1 (0.51) | ALDH1A1MAPTUSP2ALOX15MAPK1 | |
| SCHEMBL29044113 | 0.82 | MAPT (0.57) | ALDH1A1MAPTHSD17B10SMN1; SMN2KMT2A | |
| SCHEMBL28693182 | 0.80 | TP53 (0.52) | ALDH1A1MAPTUSP2ALOX15MAPK1 | |
| SCHEMBL28686525 | 0.79 | ALDH1A1 (0.76) | ALDH1A1MAPTUSP2ALOX15MAPK1 | |
| SCHEMBL29044123 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPTUSP2ALOX15MAPK1 | |
| SCHEMBL28705162 | 0.79 | TP53 (0.55) | ALDH1A1MAPTUSP2ALOX15MAPK1 | |
| SCHEMBL29044109 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTUSP2ALOX15MAPK1 | |
| SCHEMBL29044117 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MAPTUSP2ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057626-B | Indole-2, 3-dione derivative, preparation method thereof and anti-liver cancer drug for inhibiting RECQL4 specific expression | 山东第一医科大学(山东省医学科学院) | 2023-06-30 | — | — | CN | disclosed |