Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 11/20 | 0.55 |
| ▸ | RAB9A | P51151 | 10/20 | 0.55 |
| ▸ | MAPT | P10636 | 10/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29044461 | 0.85 | GAA (0.59) | GAAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL29044470 | 0.85 | MAPT (0.47) | GAAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL280339 | 0.81 | GAA (0.55) | GAAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL29044476 | 0.81 | SRC (0.42) | GAAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL29044473 | 0.81 | SRC (0.39) | GAAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL29044460 | 0.80 | LMNA (0.57) | GAAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL6273265 | 0.79 | CCR4 (0.50) | GAAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL29044455 | 0.79 | SRC (0.48) | GAAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL260704 | 0.76 | GAA (0.52) | GAAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL29044466 | 0.75 | MAPT (0.65) | GAAALDH1A1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116531373-B | Thiazole compound, pharmaceutical composition and application thereof | 上海日馨医药科技股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-116531373-A | Thiazole compound, pharmaceutical composition and application thereof | 上海日馨医药科技股份有限公司 | 2023-08-04 | — | — | CN | disclosed |