Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 11/20 | 0.55 |
| ▸ | RAB9A | P51151 | 10/20 | 0.55 |
| ▸ | NPC1 | O15118 | 10/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.55 |
| ▸ | MEN1 | O00255 | 9/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29044443 | 0.87 | ALDH1A1 (0.43) | GAAALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL29044444 | 0.85 | GAA (0.59) | GAAALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL29044449 | 0.85 | MAPT (0.47) | GAAALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL30522185 | 0.85 | MAPT (0.47) | GAAALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL29044438 | 0.80 | ALDH1A1 (0.54) | GAAALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL280339 | 0.78 | GAA (0.55) | GAAALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL260704 | 0.76 | GAA (0.52) | GAAALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL29044466 | 0.72 | MAPT (0.65) | GAAALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL25804386 | 0.72 | ALDH1A1 (0.69) | GAAALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL29044457 | 0.72 | MAOB (0.57) | ALDH1A1RAB9ANPC1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116531373-B | Thiazole compound, pharmaceutical composition and application thereof | 上海日馨医药科技股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-116531373-A | Thiazole compound, pharmaceutical composition and application thereof | 上海日馨医药科技股份有限公司 | 2023-08-04 | — | — | CN | disclosed |