Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 12/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30488014 | 1.00 | MAPT (0.53) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL1554000 | 0.90 | MAPT (0.58) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL5017694 | 0.85 | ADORA2A (0.56) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL30108078 | 0.82 | MAPT (0.50) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL30353595 | 0.82 | ADORA2A (0.50) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL717572 | 0.82 | MAPT (0.54) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL5022515 | 0.82 | MAPT (0.50) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL718474 | 0.82 | HSP90AA1 (0.54) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL20400583 | 0.78 | ADORA2A (0.48) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL5022427 | 0.78 | ADORA2B (0.49) | MAPTHSD17B10KDM4EALDH1A1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113061116-B | Aminopyrimidine compound, preparation method, composition and application thereof | 上海医药工业研究院 | 2023-07-25 | — | — | CN | disclosed |