Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 15/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554000 | 0.87 | MAPT (0.58) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL29044796 | 0.82 | MAPT (0.53) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL30488014 | 0.82 | MAPT (0.53) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL718474 | 0.79 | HSP90AA1 (0.54) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL717572 | 0.79 | MAPT (0.54) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL30353595 | 0.79 | ADORA2A (0.50) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL20400583 | 0.76 | ADORA2A (0.48) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL30353576 | 0.76 | ALDH1A1 (0.58) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL7145784 | 0.76 | KDM4E (0.54) | MAPTHSD17B10KDM4EALDH1A1BLM | |
| SCHEMBL928413 | 0.76 | ADORA2A (0.58) | MAPTHSD17B10ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |