Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26668651 | 0.94 | MTNR1A (0.37) | MTNR1AMTNR1BL3MBTL1HPGDALDH1A1 | |
| SCHEMBL26668644 | 0.88 | MTNR1A (0.39) | MTNR1AMTNR1BL3MBTL1HPGDALDH1A1 | |
| SCHEMBL24936189 | 0.84 | KCNH2 (0.50) | KCNH2 | |
| SCHEMBL30522714 | 0.84 | KCNH2 (0.50) | KCNH2 | |
| SCHEMBL1972529 | 0.80 | MTNR1A (0.54) | MTNR1AMTNR1BL3MBTL1HPGDALDH1A1 | |
| SCHEMBL24936303 | 0.77 | CA9 (0.42) | L3MBTL1ALDH1A1SMN1; SMN2PKMHCRTR1 | |
| SCHEMBL29045177 | 0.76 | HPGD (0.36) | MTNR1AMTNR1BL3MBTL1HPGDALDH1A1 | |
| SCHEMBL31355169 | 0.76 | KMT2A (0.36) | L3MBTL1ALDH1A1LMNASMN1; SMN2AURKA | |
| SCHEMBL26668652 | 0.73 | KCNH2 (0.51) | L3MBTL1HPGDALDH1A1AURKALCK | |
| SCHEMBL17449219 | 0.71 | CYP3A4 (0.43) | L3MBTL1ALDH1A1SMN1; SMN2HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116546974-A | 5-heteroaryl-1H-pyrazol-3-amine derivatives | 住友制药株式会社 | 2023-08-04 | — | — | CN | disclosed |