Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 5/20 | 0.38 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29413709 | 0.89 | BTK (0.40) | BTKCTSSCTSKKMT2AHDAC4 | |
| SCHEMBL8286493 | 0.82 | BTK (0.46) | BTKCTSSCTSKKMT2AHDAC4 | |
| SCHEMBL5848683 | 0.79 | CTSK (0.42) | BTKCTSSCTSKKMT2AHDAC4 | |
| SCHEMBL6477906 | 0.78 | CTSK (0.44) | BTKCTSSCTSKKMT2AHDAC4 | |
| SCHEMBL1294357 | 0.77 | BTK (0.49) | BTKCTSSCTSKKMT2AHDAC4 | |
| SCHEMBL8281707 | 0.77 | BTK (0.49) | BTKCTSSCTSKKMT2AHDAC4 | |
| SCHEMBL27141290 | 0.77 | BTK (0.49) | BTKCTSSCTSKKMT2AHDAC4 | |
| SCHEMBL8554341 | 0.76 | CTSK (0.41) | BTKCTSSCTSKKMT2AGAA | |
| SCHEMBL14011490 | 0.76 | GAA (0.47) | BTKCTSSCTSKKMT2AHDAC4 | |
| SCHEMBL8288558 | 0.75 | BTK (0.41) | BTKCTSSCTSKKMT2AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547287-A | Inhibitors of APOL1 and methods of use thereof | 弗特克斯药品有限公司 | 2023-08-04 | — | — | CN | disclosed |