Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.56 |
| ▸ | THRA | P10827 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596410 | 0.87 | THRB (0.59) | THRBTHRAHPGDHTTTSHR | |
| SCHEMBL15899562 | 0.83 | HPGD (0.44) | HPGDHTTL3MBTL1TSHRMTNR1A | |
| SCHEMBL15899563 | 0.82 | HPGD (0.39) | HPGDHTTL3MBTL1TSHRMTNR1A | |
| SCHEMBL30830303 | 0.82 | THRB (0.57) | THRBTHRAHPGDTSHRTYMS | |
| SCHEMBL146450 | 0.80 | THRB (0.70) | THRBTHRAHPGDL3MBTL1TSHR | |
| SCHEMBL31679622 | 0.80 | THRB (0.52) | THRBTHRAHPGDHTTTYMS | |
| SCHEMBL29280879 | 0.79 | THRB (0.61) | THRBTHRAHPGDL3MBTL1MTNR1A | |
| SCHEMBL27093552 | 0.79 | THRB (0.60) | THRBTHRAHPGDTSHRTYMS | |
| SCHEMBL11240569 | 0.78 | THRB (0.63) | THRBTHRAHPGDTYMSHSD17B10 | |
| SCHEMBL6219545 | 0.77 | THRB (0.61) | THRBTHRAHPGDL3MBTL1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514679-A | Palladium-catalyzed sp with low-cost and high-efficiency quaternary ammonium nitrate as oxidant 2 And sp (sp) 3 Carbon hydrogen bond alkenylation method | 南京工业大学 | 2023-08-01 | — | — | CN | disclosed |