Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2384477 | 0.93 | ITGA4 (0.44) | JAK2S1PR4ALDH1A1LMNAHSP90AA1 | |
| SCHEMBL2386629 | 0.92 | ITGA4 (0.41) | JAK2S1PR4ALDH1A1LMNAHSP90AA1 | |
| SCHEMBL6459262 | 0.91 | ACE (0.49) | ALDH1A1NPSR1ACEITGA4ITGB7 | |
| SCHEMBL2385002 | 0.91 | ACE (0.49) | ALDH1A1NPSR1ACEITGA4ITGB7 | |
| SCHEMBL7389438 | 0.87 | ITGA4 (0.55) | ALDH1A1ACEITGA4ITGB7AKT1 | |
| SCHEMBL2386632 | 0.83 | ITGA4 (0.45) | ALDH1A1LMNAACEITGA4ITGB7 | |
| SCHEMBL2385485 | 0.83 | ITGA4 (0.49) | ALDH1A1LMNATHRBACEITGA4 | |
| SCHEMBL2386839 | 0.83 | ITGA4 (0.47) | ALDH1A1ACEITGA4ITGB7AKT1 | |
| SCHEMBL2384488 | 0.83 | ITGA4 (0.42) | ALDH1A1LMNAACEITGA4ITGB7 | |
| SCHEMBL2385845 | 0.83 | ITGA4 (0.43) | JAK2S1PR4ALDH1A1LMNAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1980622-B1 | METHOD FOR PRODUCTION OF AN OPTICALLY ACTIVE BIPHENYLALANINE COMPOUND OR SALT OR ESTER THEREOF | SUMITOMO CHEMICAL CO (JP) | 2010-08-18 | — | — | EP | disclosed |
| EP-1980622-A1 | METHOD FOR PRODUCTION OF OPTICALLY ACTIVE BIPHENYLALANINE COMPOUND OR SALT OR ESTER THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-10-15 | — | — | EP | disclosed |