Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2385002 | 1.00 | ACE (0.49) | ACEITGA4ITGB7CTSSCTSL | |
| SCHEMBL2385485 | 0.92 | ITGA4 (0.49) | ACEITGA4ITGB7CTSSCTSL | |
| SCHEMBL2904541 | 0.91 | JAK2 (0.42) | ACEITGA4ITGB7CTSSCTSL | |
| SCHEMBL2386632 | 0.90 | ITGA4 (0.45) | ACEITGA4ITGB7CTSSCTSL | |
| SCHEMBL5030051 | 0.90 | ITGA4 (0.45) | ACEITGA4ITGB7CTSSCTSL | |
| SCHEMBL7389438 | 0.89 | ITGA4 (0.55) | ACEITGA4ITGB7CTSSAKT1 | |
| SCHEMBL2907748 | 0.88 | GPR132 (0.51) | ACEPPARGMMEACE2 | |
| SCHEMBL2388324 | 0.87 | ATM (0.47) | ACEITGA4ITGB7CTSSCTSL | |
| SCHEMBL2385034 | 0.87 | ITGA4 (0.45) | ACEITGA4ITGB7CTSSCTSL | |
| SCHEMBL2385950 | 0.87 | ITGA4 (0.47) | ACEITGA4ITGB7CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050187409-A1 | Inhibitors of RNase P proteins as antibacterial compounds | POWERS GORDON D (US) | 2005-08-25 | — | — | US | disclosed |
| WO-2005039494-A2 | INHIBITORS OF RNASE P PROTEINS AS ANTIBACTERIAL COMPOUNDS | MESSAGE PHARMACEUTICALS, INC. (US) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187409-A1 | Inhibitors of RNase P proteins as antibacterial compounds | RNASEH1, RNASEL, RNASE1 | ACE 608/4885ITGA4 4804/4885ITGB7 4835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.