Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | BPTF | Q12830 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036164 | 1.00 | SIRT6 (0.58) | SIRT6ADRB1BPTFMAPTALDH1A1 | |
| SCHEMBL29723778 | 1.00 | SIRT6 (0.58) | SIRT6ADRB1BPTFMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL30354933 | 0.98 | SIRT6 (0.57) | SIRT6ADRB1BPTFMAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL22495374 | 0.88 | BPTF (0.48) | SIRT6ADRB1BPTFMAPTPOLB | |
| SCHEMBL12939934 | 0.84 | MAPT (0.58) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL10036155 | 0.80 | SIRT6 (0.63) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL17630781 | 0.80 | MAPT (0.53) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL29466332 | 0.78 | MAPT (0.50) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL6716676 | 0.77 | MAPT (0.58) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL3549925 | 0.77 | MAPT (0.58) | SIRT6ADRB1MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142748-B | Pyrazolopyrimidine compound, and preparation method and application thereof | 上海医药集团股份有限公司 | 2023-07-04 | — | — | CN | disclosed |