Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 14/20 | 0.65 |
| ▸ | EPOR | P19235 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | IL1RN | P18510 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL733465 | 0.84 | LTA4H (0.55) | LTA4HNPC1SMN1; SMN2LMNA | |
| SCHEMBL733464 | 0.84 | LTA4H (0.55) | LTA4HNPC1SMN1; SMN2LMNA | |
| SCHEMBL735424 | 0.84 | LTA4H (0.55) | LTA4HNPC1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL734142 | 0.83 | LTA4H (0.54) | LTA4HNPC1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL734141 | 0.83 | LTA4H (0.54) | LTA4HNPC1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL736449 | 0.83 | LTA4H (0.54) | LTA4HNPC1SMN1; SMN2LMNA | |
| SCHEMBL1833133 | 0.81 | LTA4H (0.54) | LTA4HNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL1833135 | 0.81 | LTA4H (0.54) | LTA4HNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6162332 | 0.81 | LTA4H (0.74) | LTA4HEPORNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7921142 | 0.81 | LTA4H (0.74) | LTA4HEPORNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304502-A | FOXM1 inhibitor and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2022-11-08 | — | — | CN | disclosed |