Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.74 |
| ▸ | LAP3 | P28838 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 4/20 | 0.60 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | EPOR | P19235 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2058710 | 1.00 | LTA4H (0.74) | LTA4HLAP3PPARGLNPEPMAOB | |
| SCHEMBL7921142 | 1.00 | LTA4H (0.74) | LTA4HLAP3PPARGLNPEPMAOB | |
| Hydrochloric Acid SCHEMBL3497991 | 0.99 | LTA4H (0.73) | LTA4HLAP3PPARGLNPEPMAOB | |
| Hydrochloric Acid SCHEMBL3499496 | 0.99 | LTA4H (0.73) | LTA4HLAP3PPARGLNPEPMAOB | |
| Hydrochloric Acid SCHEMBL3497988 | 0.99 | LTA4H (0.73) | LTA4HLAP3PPARGLNPEPMAOB | |
| Phenylalanine Methyl Ester SCHEMBL28633098 | 0.96 | LTA4H (0.70) | LTA4HLAP3PPARGLNPEPPPARA | |
| Butylamine SCHEMBL8391542 | 0.91 | LTA4H (0.63) | LTA4HLAP3PPARGLNPEPEPOR | |
| SCHEMBL16607620 | 0.90 | LTA4H (0.67) | LTA4HLAP3PPARGLNPEPMAOB | |
| SCHEMBL6561218 | 0.89 | LTA4H (0.73) | LTA4HLAP3PPARGLNPEPMAOB | |
| SCHEMBL1855604 | 0.89 | LTA4H (0.73) | LTA4HLAP3PPARGLNPEPMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0828754-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038471-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1996-12-05 | — | — | WO | disclosed |