SCHEMBL29045993

SCHEMBL29045993

Cc1ccc(-n2c(O)nnc2S)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.37
POLB P06746 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
ALDH1A1 P00352 5/20 0.35
MAPT P10636 4/20 0.35
NOTUM Q6P988 2/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
HPGD P15428 2/20 0.35
LMNA P02545 1/20 0.35
HSP90AA1 P07900 1/20 0.35
XBP1 P17861 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28796923 0.81 MAPT (0.36) KDM4EL3MBTL1ALOX15POLBALDH1A1
SCHEMBL7806028 0.80 KMT2A (0.38) KDM4EL3MBTL1TSHRCYP3A4CYP2D6
SCHEMBL13703856 0.80 KDM4E (0.47) KDM4EL3MBTL1ALOX15TSHRTDP1
SCHEMBL14345465 0.78 ALDH1A1 (0.48) KDM4EL3MBTL1ALOX15TSHRCYP3A4
SCHEMBL931691 0.75 TSHR (0.54) KDM4EL3MBTL1ALOX15TSHRPOLB
SCHEMBL11996348 0.74 L3MBTL1 (0.42) KDM4EL3MBTL1ALOX15TSHRTDP1
SCHEMBL931765 0.74 ESR1 (0.46) KDM4EL3MBTL1ALOX15TSHRTDP1
SCHEMBL11996161 0.73 KDM4E (0.41) KDM4EL3MBTL1ALOX15TSHRTDP1
SCHEMBL8287013 0.73 KDM4E (0.41) KDM4EL3MBTL1ALOX15TSHRTDP1
SCHEMBL20869675 0.72 HSD17B10 (0.58) KDM4EL3MBTL1ALOX15TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114855229-B Electroplating solution and formula for co-plating blind hole through hole of electronic circuit 电子科技大学 2023-05-19 CN claimed
CN-114855229-B Electroplating solution and formula for co-plating blind hole through hole of electronic circuit 电子科技大学 2023-05-19 CN disclosed
CN-114855229-B Electroplating solution and formula for co-plating blind hole through hole of electronic circuit 电子科技大学 2023-05-19 CN disclosed