SCHEMBL29046355

SCHEMBL29046355

O=c1cc(OCCCN2CCNCC2)c2ccccc2o1

nearest known ligand 0.73

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.69
KCNA3 P22001 1/20 0.60
CYP19A1 P11511 1/20 0.54
XDH P47989 1/20 0.52
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA9 Q16790 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29794227 1.00 MAOB (0.69) MAOBKCNA3CYP19A1XDHCA12
SCHEMBL29046356 0.79 MAOB (0.57) MAOB
SCHEMBL17865166 0.79
SCHEMBL17844943 0.79 ALDH1A1 (0.60)
Hydrochloric Acid SCHEMBL17847593 0.78
SCHEMBL3918076 0.78 KCNA3 (0.62) MAOBKCNA3CYP19A1CA12CA1
SCHEMBL9390589 0.77 KCNA3 (0.62) MAOBKCNA3XDH
SCHEMBL8805345 0.77 MAOB (0.54) MAOB
SCHEMBL6599915 0.76 KCNA3 (0.72) MAOBKCNA3CYP19A1CA12CA1
SCHEMBL3912517 0.76 KCNA3 (0.72) MAOBKCNA3CYP19A1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114751885-B Coumarin compound containing isopropanolamine structure and preparation method and application thereof 贵州大学 2023-08-08 CN claimed
CN-114751885-A Coumarin compound containing isopropanolamine structure and preparation method and application thereof 贵州大学 2022-07-15 CN claimed
CN-114751885-B Coumarin compound containing isopropanolamine structure and preparation method and application thereof 贵州大学 2023-08-08 CN disclosed
CN-114751885-A Coumarin compound containing isopropanolamine structure and preparation method and application thereof 贵州大学 2022-07-15 CN disclosed