Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8686164 | 0.84 | HTR2A (0.52) | KDM4ECYP1A2CYP3A4CYP2D6HTR2A | |
| SCHEMBL6253491 | 0.81 | HTR2A (0.60) | KDM4ECYP1A2CYP3A4CYP2D6HTR2A | |
| SCHEMBL8806438 | 0.79 | KCNH2 (0.62) | MAOBHTR2A | |
| SCHEMBL8807400 | 0.79 | HTR2A (0.57) | KDM4ECYP1A2CYP3A4CYP2D6HTR2A | |
| SCHEMBL8804878 | 0.79 | DRD2 (0.61) | MAOB | |
| SCHEMBL1583103 | 0.78 | KDM4E (0.69) | MAOBKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8805189 | 0.77 | HTR2A (0.55) | KDM4ECYP1A2CYP3A4CYP2D6HTR2A | |
| SCHEMBL8805723 | 0.77 | HTR2A (0.65) | KDM4ECYP1A2CYP3A4CYP2D6HTR2A | |
| SCHEMBL29794227 | 0.77 | MAOB (0.69) | MAOB | |
| SCHEMBL29046355 | 0.77 | MAOB (0.69) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751936-A1 | NEW 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES USEFUL AS MEDICAMENTS ACTING ON THE GLUTAMATE RECEPTOR | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-01-08 | — | — | EP | claimed |
| WO-1995025721-A1 | NEW 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES USEFUL AS MEDICAMENTS ACTING ON THE GLUTAMATE RECEPTOR | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-09-28 | — | — | WO | claimed |
| EP-0751936-A1 | NEW 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES USEFUL AS MEDICAMENTS ACTING ON THE GLUTAMATE RECEPTOR | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995025721-A1 | NEW 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES USEFUL AS MEDICAMENTS ACTING ON THE GLUTAMATE RECEPTOR | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-09-28 | — | — | WO | disclosed |