Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19511360 | 0.92 | ALDH1A1 (0.45) | LMNAALDH1A1CYP3A4TSHRFDPS | |
| SCHEMBL28049401 | 0.82 | FFAR1 (0.49) | LMNAFFAR1FFAR4GMNNPOLB | |
| SCHEMBL28049400 | 0.82 | FFAR1 (0.45) | LMNAFFAR1FFAR4GMNNPOLB | |
| SCHEMBL28049412 | 0.82 | FFAR1 (0.49) | LMNAFFAR1FFAR4GMNNPOLB | |
| SCHEMBL28049354 | 0.82 | FFAR1 (0.49) | LMNAFFAR1FFAR4GMNNPOLB | |
| SCHEMBL28049424 | 0.82 | FFAR1 (0.49) | LMNAFFAR1FFAR4GMNNPOLB | |
| SCHEMBL5594684 | 0.79 | LMNA (0.41) | LMNAALDH1A1FFAR1FFAR4SPHK1 | |
| SCHEMBL2052115 | 0.79 | LMNA (0.50) | LMNAALDH1A1FFAR1FFAR4HSD17B10 | |
| SCHEMBL8143856 | 0.78 | FFAR1 (0.57) | LMNAFFAR1FFAR4CYP2D6SPHK1 | |
| SCHEMBL6438441 | 0.78 | FFAR1 (0.45) | LMNAFFAR1FFAR4GMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601152-A | Pyrrolopyridine-anilines for the treatment of cognitive dysfunction | 恩福莱克逊治疗有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-116549389-A | Intranasal adrenergic formulations and methods of treating diseases | 爱奇司治疗公司 | 2023-08-08 | — | — | CN | disclosed |