Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.48 |
| ▸ | PPARG | P37231 | 15/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 16/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29046573 | 1.00 | PPARD (0.48) | PPARDPPARGFFAR1PPARA | |
| SCHEMBL10011429 | 0.88 | PPARD (0.62) | PPARDPPARGFFAR1PPARA | |
| SCHEMBL16449097 | 0.83 | FFAR1 (0.50) | PPARDPPARGFFAR1PPARA | |
| SCHEMBL18526217 | 0.83 | FFAR1 (0.50) | PPARDPPARGFFAR1PPARA | |
| SCHEMBL16123797 | 0.83 | FFAR1 (0.50) | PPARDPPARGFFAR1PPARA | |
| SCHEMBL21178299 | 0.79 | PPARG (0.38) | PPARDPPARGFFAR1PPARA | |
| SCHEMBL16499628 | 0.79 | PPARG (0.38) | PPARDPPARGFFAR1PPARA | |
| SCHEMBL21270524 | 0.76 | CA2 (0.38) | PPARDPPARG | |
| SCHEMBL21270522 | 0.76 | CA2 (0.38) | PPARDPPARG | |
| SCHEMBL3718724 | 0.75 | HSD11B1 (0.41) | PPARDPPARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547270-A | 4- (2-fluoro-4-methoxy-5-3- (((1-methylcyclobutyl) methyl) carbamoyl) bicyclo [2.2.1] hept-2-yl) carbamoyl) phenoxy) -1-methylcyclohexane-1-carboxylic acid derivatives and similar compounds as RXFP1 modulators for the treatment of heart failure | 阿斯利康(瑞典)有限公司 | 2023-08-04 | — | — | CN | disclosed |