P-Cresol

P-Cresol

SCHEMBL29047183

Cc1ccc(O)cc1.NC(=O)NCCCCS(=O)(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 4/20 0.40
LMNA P02545 1/20 0.40
ALB P02768 1/20 0.40
CYP2C9 P11712 1/20 0.40
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
SLC6A5 Q9Y345 1/20 0.39
ACHE P22303 1/20 0.38
EPHX2 P34913 1/20 0.38
CYP2C19 P33261 1/20 0.37
HPGD P15428 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL28888307 0.87 ALDH1A1 (0.43) RAB9AALDH1A1LMNACYP2C9CYP2C19
Toluene SCHEMBL29092586 0.81 ALDH1A1 (0.39) RAB9AALDH1A1LMNACYP2C9CYP2C19
SCHEMBL10725195 0.81 ALDH1A1 (0.59) L3MBTL1ALDH1A1LMNAALBCYP2C9
SCHEMBL30451388 0.80 APP (0.46) ALDH1A1LMNAEPHX2CYP2C19
P-Cresol SCHEMBL27759325 0.80 HPGD (0.54) RAB9AL3MBTL1ALDH1A1LMNAALB
SCHEMBL10002627 0.77 APP (0.46) ALDH1A1LMNAEPHX2CYP2C19
SCHEMBL25840780 0.72 ALDH1A1 (0.59) RAB9AALDH1A1CYP2C9CYP2C19
SCHEMBL15927264 0.71 HTT (0.49) L3MBTL1LMNACYP2C19
SCHEMBL17195403 0.71 MAPT (0.55) RAB9AALDH1A1LMNACYP2C9CYP2C19
SCHEMBL5842513 0.70 KDM4E (0.38) ALDH1A1LMNAEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113943717-B CYP2C9 mutant, corresponding nucleic acid segment and application thereof 北京医院 2023-08-08 CN disclosed