Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10002627 | 0.95 | APP (0.46) | APPEPHX2LMNASLC6A6CYP2C19 | |
| SCHEMBL8664606 | 0.86 | LMNA (0.42) | APPEPHX2LMNASLC6A6CYP2C19 | |
| SCHEMBL5842513 | 0.83 | KDM4E (0.38) | EPHX2LMNAALOX15KDM4EMAPK1 | |
| SCHEMBL1837224 | 0.83 | KDM4E (0.48) | LMNABLMKDM4EMAPK1HIF1A | |
| Toluene SCHEMBL28888307 | 0.82 | ALDH1A1 (0.43) | LMNACYP2C19ALDH1A1MEN1KMT2A | |
| SCHEMBL28904376 | 0.81 | KDM4E (0.41) | EPHX2KDM4EMAPK1HIF1AALDH1A1 | |
| P-Cresol SCHEMBL29047183 | 0.80 | RAB9A (0.41) | EPHX2LMNACYP2C19ALDH1A1 | |
| SCHEMBL4100132 | 0.80 | ALOX15 (0.56) | APPEPHX2LMNASLC6A6CYP2C19 | |
| SCHEMBL1839119 | 0.80 | KDM4E (0.52) | KDM4EMAPK1HIF1AALDH1A1SMN1; SMN2 | |
| SCHEMBL1309360 | 0.80 | KDM4E (0.52) | KDM4EMAPK1HIF1AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117686604-A | Method for determining metabolic product | 益诺思生物技术南通有限公司 | 2024-03-12 | — | — | CN | claimed |
| CN-121717808-B | Imidazopyridine derivative and preparation method, pharmaceutical composition and application thereof | Hunan Xianshi Pharmaceutical Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-122070287-A | IRAK 4-targeted degradation agent compound and application thereof | 江苏先声药业有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-119350323-B | N-sulfonyl amide nitrogen-containing fused heterocycle compounds targeting p53 mutation and application thereof | 上海宇道生物技术有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-120092002-A | Condensed heteroaromatics, composition and application thereof | 海南先声再明医药股份有限公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-119907796-A | Amide compound, composition and application thereof | 海南先声再明医药股份有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-119841799-A | Polyphenol compound, and preparation method and application thereof | 复旦大学 | 2025-04-18 | — | — | CN | disclosed |
| CN-115093408-B | Benzylamine-containing 5, 6-heteroaromatic compounds useful against mycobacterial infections | 盐野义制药株式会社 | 2025-03-11 | — | — | CN | disclosed |
| CN-119604500-A | Heterocyclic pyrimidine compound and application thereof | 海南先声再明医药股份有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-113717198-B | Process for preparing substituted polycyclic pyridone derivatives and crystals thereof | 盐野义制药株式会社 | 2025-03-07 | — | — | CN | disclosed |
| CN-116656771-A | Detection method for judging whether test object is SLC transporter substrate or inhibitor | 江苏鼎泰药物研究(集团)股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-113648318-B | Use of enhancing cell thermogenesis and treating diseases | 中国科学院上海营养与健康研究所 | 2023-08-25 | — | — | CN | disclosed |
| CN-113105486-B | Boric acid ester compound and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 南京师范大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-116589469-A | 1H-pyrazole derivatives as Syk and VEGFR2 double-target inhibitors and application thereof | 苏州欧康维视生物科技有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-113943717-B | CYP2C9 mutant, corresponding nucleic acid segment and application thereof | 北京医院 | 2023-08-08 | — | — | CN | disclosed |
| CN-116529390-A | Method for evaluating excretion of test substance by human hepatocyte-like cells | JSR株式会社 | 2023-08-01 | — | — | CN | disclosed |
| CN-114755335-B | Quantitative detection method for pyrimidine derivative 1D228 enantiomer in biological sample | 广东莱恩医药研究院有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-116466000-A | Method for rapidly determining 176 PPCPs content in source water | 福建省产品质量检验研究院(福建省缺陷产品召回技术中心) | 2023-07-21 | — | — | CN | disclosed |
| CN-116410127-A | Multi-target anti-schizophrenia phenylpyridine piperazine compound, and preparation method and application thereof | 上海医药工业研究院有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-114364679-B | 1H-pyrazole derivatives as Syk and VEGFR2 double-target inhibitors and application thereof | 苏州欧康维视生物科技有限公司 | 2023-06-09 | — | — | CN | disclosed |