Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 9/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.39 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30546950 | 1.00 | CLCN2 (0.51) | CLCN2RXFP1HTTALDH1A1CYP3A4 | |
| SCHEMBL30546975 | 0.88 | LMNA (0.45) | RXFP1MAPK14LMNATAS2R14RECQL | |
| SCHEMBL29047734 | 0.88 | RXFP1 (0.46) | RXFP1MAPK14LMNATAS2R14CRACR2A | |
| SCHEMBL29047705 | 0.88 | LMNA (0.45) | RXFP1MAPK14LMNATAS2R14RECQL | |
| SCHEMBL30546957 | 0.88 | RXFP1 (0.46) | RXFP1MAPK14LMNATAS2R14CRACR2A | |
| SCHEMBL30546973 | 0.87 | MAPK14 (0.49) | CLCN2RXFP1ALDH1A1MAPK14LMNA | |
| SCHEMBL29047672 | 0.87 | MAPK14 (0.49) | CLCN2RXFP1ALDH1A1MAPK14LMNA | |
| SCHEMBL30546929 | 0.86 | RECQL (0.48) | RXFP1HTTALDH1A1LMNATAS2R14 | |
| SCHEMBL29047633 | 0.86 | RECQL (0.48) | RXFP1HTTALDH1A1LMNATAS2R14 | |
| SCHEMBL29047658 | 0.84 | RXFP1 (0.57) | RXFP1ALDH1A1CYP3A4HSD17B10MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535357-A | Arylamino benzamide derivative containing substituted pyrazole structure, preparation method and application | 西北农林科技大学 | 2023-08-04 | — | — | CN | disclosed |