Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521258 | 0.82 | NPC1 (0.58) | ALDH1A1KDM4EHSP90AA1KMT2AMEN1 | |
| SCHEMBL11518562 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HSP90AA1KMT2AMEN1LMNA | |
| SCHEMBL11520323 | 0.80 | HDAC1 (0.55) | ALDH1A1KDM4EHSP90AA1KMT2AMEN1 | |
| SCHEMBL11518707 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSP90AA1KMT2AMEN1 | |
| SCHEMBL29047626 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL24534671 | 0.76 | MEN1 (0.74) | ALDH1A1KDM4EHSP90AA1KMT2AMEN1 | |
| SCHEMBL29047638 | 0.75 | POLB (0.56) | ALDH1A1KDM4EHSP90AA1KMT2AMEN1 | |
| SCHEMBL29047570 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL11332130 | 0.75 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSP90AA1KMT2AMEN1 | |
| SCHEMBL29047565 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947931-B | Thiazole amide compound, preparation method thereof, pharmaceutical composition and application | 中国科学院上海有机化学研究所 | 2023-07-07 | — | — | CN | disclosed |