SCHEMBL29047783

SCHEMBL29047783

c1ccc2c(c1)-c1ccccc1C2[C]1CCCC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.43
BCHE P06276 1/20 0.39
ACHE P22303 1/20 0.39
GPR3 P46089 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
NCOR2 Q9Y618 1/20 0.38
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
TSHR P16473 2/20 0.36
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
RET P07949 1/20 0.34
IDO1 P14902 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29047784 0.98 BCHE (0.42) HTR2ABCHEACHEGPR3HDAC3
SCHEMBL29116619 0.69 HTR2A (0.50) HTR2AGPR3HDAC3HDAC4HDAC7
SCHEMBL29490167 0.67 HTR2A (0.48) HTR2ABCHEACHEGPR3HDAC3
SCHEMBL29370508 0.67 LMNA (0.54) HTR2AGPR3CYP1A2RETADRA2C
SCHEMBL9297178 0.67 HTR2A (0.48) HTR2ABCHEACHEGPR3HDAC3
SCHEMBL25171318 0.67 LMNA (0.54) HTR2AGPR3CYP1A2RETADRA2C
SCHEMBL1304934 0.67 HTR2A (0.48) HTR2ABCHEACHEGPR3HDAC3
SCHEMBL70993 0.67 LMNA (0.54) HTR2AGPR3CYP1A2RETADRA2C
SCHEMBL353865 0.66 HTR2A (0.52) HTR2ABCHEACHEGPR3HDAC3
SCHEMBL31430380 0.66 TSHR (0.71) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116156921-A Organic electroluminescent device 长春海谱润斯科技股份有限公司 2023-05-23 CN disclosed