SCHEMBL29047784

SCHEMBL29047784

c1ccc2c(c1)-c1ccccc1C2[C]1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.42
ACHE P22303 1/20 0.42
HTR2A P28223 3/20 0.41
GPR3 P46089 1/20 0.37
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36
NCOR2 Q9Y618 1/20 0.36
TSHR P16473 2/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2A6 P11509 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29047783 0.98 HTR2A (0.43) BCHEACHEHTR2AGPR3HDAC3
SCHEMBL31621255 0.67 TSHR (0.67) TSHRCYP2A6MAOAMAOB
SCHEMBL30731351 0.67 TSHR (0.67) TSHRCYP2A6MAOAMAOB
SCHEMBL30668198 0.67 TSHR (0.67) TSHRCYP2A6MAOAMAOB
SCHEMBL29593589 0.67 TSHR (0.67) TSHRCYP2A6MAOAMAOB
SCHEMBL31135519 0.67 TSHR (0.67) TSHRCYP2A6MAOAMAOB
SCHEMBL29116619 0.67 HTR2A (0.50) HTR2AGPR3HDAC3HDAC4HDAC7
Hydrochloric Acid SCHEMBL7098252 0.67 BCHE (0.38) BCHEACHEHTR2AGPR3TSHR
SCHEMBL7098257 0.67 BCHE (0.38) BCHEACHEHTR2AGPR3TSHR
SCHEMBL4476575 0.67 PTGS2 (0.56) BCHEACHEGPR3CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116156921-A Organic electroluminescent device 长春海谱润斯科技股份有限公司 2023-05-23 CN disclosed