Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30423719 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2HPGDMAPK1 | |
| SCHEMBL31075215 | 0.82 | MAPK1 (0.46) | ALDH1A1LMNASMN1; SMN2HPGDMAPK1 | |
| SCHEMBL31075420 | 0.82 | MAPK1 (0.46) | ALDH1A1LMNASMN1; SMN2HPGDMAPK1 | |
| SCHEMBL26618242 | 0.81 | MAPK1 (0.41) | ALDH1A1LMNASMN1; SMN2HPGDMAPK1 | |
| SCHEMBL30415267 | 0.81 | MAPK1 (0.41) | ALDH1A1LMNASMN1; SMN2HPGDMAPK1 | |
| SCHEMBL25984988 | 0.76 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2HPGDMAPK1 | |
| SCHEMBL10669079 | 0.75 | ALDH1A1 (0.48) | ALDH1A1LMNASMN1; SMN2HPGDMAPK1 | |
| SCHEMBL29047858 | 0.75 | SLC5A1 (0.41) | ALDH1A1TSHR | |
| SCHEMBL29224384 | 0.74 | ALDH1A1 (0.48) | ALDH1A1LMNASMN1; SMN2HPGDMAPK1 | |
| SCHEMBL29047859 | 0.74 | MEN1 (0.42) | ALDH1A1LMNASMN1; SMN2HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157154-A | Plasma kallikrein inhibitors | 默沙东有限责任公司 | 2023-05-23 | — | — | CN | disclosed |