Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10665313 | 0.82 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2TSHRPOLB | |
| SCHEMBL24966161 | 0.81 | LMNA (0.57) | ALDH1A1LMNASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL10668049 | 0.81 | ALDH1A1 (0.55) | ALDH1A1LMNASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL10959131 | 0.81 | CA5A (0.52) | ALDH1A1LMNASMN1; SMN2TSHRPOLB | |
| SCHEMBL25984988 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL10568392 | 0.78 | CYP1A2 (0.44) | ALDH1A1LMNASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL31075420 | 0.78 | MAPK1 (0.46) | ALDH1A1LMNASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL31075215 | 0.78 | MAPK1 (0.46) | ALDH1A1LMNASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL29224384 | 0.77 | ALDH1A1 (0.48) | ALDH1A1LMNASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL29047832 | 0.75 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4789680-A | Aralkyltriazole compounds | CIBA-GEIGY CORPORATION (US) | 1988-12-06 | — | — | US | disclosed |