Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | HPGD | P15428 | 5/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.73 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28587261 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| Lomefloxacin SCHEMBL1650432 | 0.85 | KDM4E (0.96) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| Lomefloxacin SCHEMBL34610 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| Lomefloxacin SCHEMBL29388501 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| Lomefloxacin SCHEMBL9226104 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| Lomefloxacin SCHEMBL133835 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL16518622 | 0.85 | KDM4E (0.85) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| Lomefloxacin SCHEMBL34609 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| Lomefloxacin SCHEMBL29895425 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| Lomefloxacin SCHEMBL8912235 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112824397-B | Lomefloxacin propenone derivative and preparation method and application thereof | 河南大学 | 2023-08-11 | — | — | CN | disclosed |